A 39-year-old woman underwent bronchoscopy because of shortness of breath and audible breathing upon exertion. An advanced tracheobronchopathia osteochondroplastica was diagnosed. Twenty years later, the woman's health status is stable, she has no cough or excessive mucous production, but she does suffer from effort dyspnea. Difficulties may arise if there is need for intubation in patients with tracheobronchopathia osteochondroplastica because of the nodules protruding inward from the cartilage rings.